基于MOFs材料的样品预处理-电色谱联用技术的开发及其在环境中痕量PCBs分析中的应用

项目名称： 基于MOFs材料的样品预处理-电色谱联用技术的开发及其在环境中痕量PCBs分析中的应用

项目编号： No.21275053

项目类型： 面上项目

立项/批准年度： 2013

项目学科： 数理科学和化学

项目作者： 李保会

作者单位： 华北电力大学（保定）

项目金额： 78万元

中文摘要： 多氯联苯(PCBs)因其对环境的污染特性以及对生物体的致病、致畸、致癌特性而迫切需要发展高选择性、高灵敏度的分离分析方法。本课题拟将MOFs用于毛细管电泳中，制备基于MOFs的固相萃取柱及毛细管电色谱柱，发展一种基于MOFs的固相萃取-电色谱分离分析新方法，以满足环境中痕量PCBs的分离检测需求。利用MOFs多变的结构以及灵活的吸附方式（如空腔的形状、大小、疏水性能等）建立PCBs的固相萃取方法；利用动态涂层的方式将MOF涂覆到毛细管壁，建立新型毛细管开管柱制备方法；采用在毛细管柱内合成MOFs晶体或将MOFs包埋于杂化柱内的方式，建立MOFs整体柱制备方法；建立一种将固相萃取技术与毛细管电色谱技术相在线联用的分析方法，富集水环境中的PCBs，使其到常规检测手段可以检测的浓度范围；通过对水环境中PCBs的分析检测，为水环境评估与治理提供简便、快捷、高灵敏度、高选择性的分析方法。

中文关键词： 样品预处理；金属有机框架结构；持久性有机污染物；联用技术；电色谱柱制备

英文摘要： In view of environmental pollution properties of polychlorinated biphenyls(PCBs) and its malgenic, carcinogenic, teratogenic behaviour to biosome and human beings, it is necessary to develop a high selectivity and sensitivity analysis and separation method for PCBs,. Herein, metal organic frameowrks(MOFs) are employed to capillary electrophoresis, and used to the preparation of solid phase extracton(SPE) and capillary electrochromatography(CEC) column. An analytical method,in which SPE is coupled with CEC hyphenation technique based on MOFs, is developed. A SPE method of PCBs is bulit by using MOFs, who has versatile three-dimensional structure and flexible adsorption mode(such as large surface area, pore shape, hydrophobicity ,etc). A CEC tubular column preparation method is developed that solid phase on the inner wall is fabricated by a dynamic coating method. A CEC monolithic column preparation method is built by synthesizing MOFs crystal in capillary or embedding MOFs micro crystal in organic inorganic hybrid materials. A enricnment method that combines off-line SPE with on-line concentraiton is developed, so that PCBs in water environment is detectable by routine UV detection. At last,one kind of simple, rapid, high sensitivity and high selectivity analytical method for water environment assessment and sup

英文关键词： sample pretreatment；metal organic frameworks；persistent organic pollutants；hyphenation technique；capillary ecectro-chromatography column