光纤端面的光栅耦合表面等离子体谐振传感器研究

项目名称： 光纤端面的光栅耦合表面等离子体谐振传感器研究

项目编号： No.61275168

项目类型： 面上项目

立项/批准年度： 2013

项目学科： 无线电电子学、电信技术

项目作者： 杨天

作者单位： 上海交通大学

项目金额： 84万元

中文摘要： 将微纳元件集成在光纤端面的研究将带来简便灵活、易于携带的光学功能器件。本项目研究两种光纤端面的光栅耦合表面等离子体谐振传感器，以实现高灵敏度微纳光学无标记生物传感技术与光纤导波技术的结合。在器件原理上，我们指出这两种新器件的传感灵敏度将远好于已报道的同类光纤端面器件。在制备工艺上，我们将研究把金膜剥离与干涉光刻技术应用于光纤端面的新工艺，使我们提出的器件能够被低成本、大批量制备，从而可以作为一次性探头。最后我们将进行检测链菌亲和素的实验，表征传感性能。本项目的研究将推动无标记生物光学传感技术往低成本、小体积、高灵敏度、操作简单、微流体集成和可体内检测的综合优势方向发展，对相关医疗诊断技术的普及有重要意义。

中文关键词： 生物传感；表面等离子体；光纤端面；；

英文摘要： The integration of micro- and nano-components on fiber facets will bring about functional optical devices which are simple, flexible and portable to work with. In this proposed project, we will study two types of grating-coupled surface plasmon resonance sensing devices on fiber facets, in order to make integration between high-sensitivity label-free nanophotonic biosensing technology and fiber-optic technology. In theory, we point out that these two types of new sensors will far outperform their existing fiber-facet sensor counterparts in sensitivity. We will also study the employment of special fabrication techniques on fiber facets, including thin gold film stripping and holography lithography, in order that these devices can be mass produced at low costs and be disposable. In the end, we will carry out streptavidin detection experiments to characterize the sensors. This project will propel the development of label-free optical biosensing technology towards the direction of having the comprehensive advantages of low cost, small footprint, high sensitivity, simple operation, microfluidic integration capacity and in vivo detection capability. It will have significant impact on making relevant medical diagnosis technologies widely accessible.

英文关键词： biosensing；surface plasmon；fiber end-facet；；