多级孔分子筛酸性调控及催化糖转化制备乳酸酯研究

项目名称： 多级孔分子筛酸性调控及催化糖转化制备乳酸酯研究

项目编号： No.U1304209

项目类型： 联合基金项目

立项/批准年度： 2014

项目学科： 数理科学和化学

项目作者： 杨晓梅

作者单位： 郑州大学

项目金额： 30万元

中文摘要： 乳酸及乳酸酯在食品、化妆品、化学品、制药及塑料工业被广泛使用。当前，乳酸及乳酸酯主要通过糖发酵制备，该法时空收率有限，且消耗大量硫酸，产生大量废盐。因此，亟需开发由糖制备乳酸及乳酸酯的高效新方法。本项目以廉价、丰富的葡萄糖转化制备乳酸酯为模型反应进行研究，该反应是一个包含醛酮糖异构、反羟醛缩合、脱水、加醇-异构等多种反应类型的多步反应过程，需要Lewis(L)酸和Br？nsted(B)酸的共同催化，且易发生副反应。因此，申请人提出用L酸和B酸酸性可调的多级孔分子筛催化该反应。通过L酸和B酸酸性的调控，实现反应产物的调控；通过孔结构的调控，提高传质效率，避免目标产物进一步转化成其它副产物，从而提高多级孔分子筛的催化活性和对目标产物的选择性。通过本项目的研究，建立分子筛的酸性质和孔结构与催化糖转化制备乳酸酯反应性能之间的关系，开发出高效的催化反应体系。

中文关键词： 糖；乳酸酯；分子筛；酸性；孔结构

英文摘要： Lactic acid (LA) and alkyl lactates are widely used in food, commodity, chemical, pharmaceutical and plastic industries. Presently, the major production process of LA and alkyl lactates is the fermentation of carbohydrates. However, the space-time yield of this method is limited, and large amounts of sulfuric acid are consumed with large amounts of salt waste as byproducts during fermentation. Therefore, it is desiderated to develop a novel and effective method to produce LA and alkyl lactates from carbohydrates. This project selects the production of alkyl lactates from cheap and abundant glucose as a model reaction. The reaction is very complex which composed of multiple reaction steps such as isomerization between aldose and ketose, retro-aldol to trioses, dehydration, addition, and etc. Both Lewis (L) and Br？nsted (B) acid sites are needed for accomplishing the reaction. Therefore, hierarchical molecular sieves with adjustable L and B acidity are employed to fulfill the reaction in this project. The product selectivity will be controlled through adjustment of L and B acidity. Meanwhile, the efficiency of mass transfer will be improved through adjusting the pore structure of molecular sieves. So the further reaction of the desired product to other byproducts will be reduced, and the catalytic activity and sel

英文关键词： Carbohydrates；Alkyl lactates；Molecular sieves；Acidity；Pore structure