In existing visual representation learning tasks, deep convolutional neural networks (CNNs) are often trained on images annotated with single tags, such as ImageNet. However, a single tag cannot describe all important contents of one image, and some useful visual information may be wasted during training. In this work, we propose to train CNNs from images annotated with multiple tags, to enhance the quality of visual representation of the trained CNN model. To this end, we build a large-scale multi-label image database with 18M images and 11K categories, dubbed Tencent ML-Images. We efficiently train the ResNet-101 model with multi-label outputs on Tencent ML-Images, taking 90 hours for 60 epochs, based on a large-scale distributed deep learning framework,i.e.,TFplus. The good quality of the visual representation of the Tencent ML-Images checkpoint is verified through three transfer learning tasks, including single-label image classification on ImageNet and Caltech-256, object detection on PASCAL VOC 2007, and semantic segmentation on PASCAL VOC 2012. The Tencent ML-Images database, the checkpoints of ResNet-101, and all the training codehave been released at https://github.com/Tencent/tencent-ml-images. It is expected to promote other vision tasks in the research and industry community.
Accurate segmentation of the prostate from magnetic resonance (MR) images provides useful information for prostate cancer diagnosis and treatment. However, automated prostate segmentation from 3D MR images still faces several challenges. For instance, a lack of clear edge between the prostate and other anatomical structures makes it challenging to accurately extract the boundaries. The complex background texture and large variation in size, shape and intensity distribution of the prostate itself make segmentation even further complicated. With deep learning, especially convolutional neural networks (CNNs), emerging as commonly used methods for medical image segmentation, the difficulty in obtaining large number of annotated medical images for training CNNs has become much more pronounced that ever before. Since large-scale dataset is one of the critical components for the success of deep learning, lack of sufficient training data makes it difficult to fully train complex CNNs. To tackle the above challenges, in this paper, we propose a boundary-weighted domain adaptive neural network (BOWDA-Net). To make the network more sensitive to the boundaries during segmentation, a boundary-weighted segmentation loss (BWL) is proposed. Furthermore, an advanced boundary-weighted transfer leaning approach is introduced to address the problem of small medical imaging datasets. We evaluate our proposed model on the publicly available MICCAI 2012 Prostate MR Image Segmentation (PROMISE12) challenge dataset. Our experimental results demonstrate that the proposed model is more sensitive to boundary information and outperformed other state-of-the-art methods.