基于共价有机骨架材料的非均相催化反应研究

项目名称： 基于共价有机骨架材料的非均相催化反应研究

项目编号： No.21202013

项目类型： 青年科学基金项目

立项/批准年度： 2013

项目学科： 有机化学

项目作者： 于金涛

作者单位： 常州大学

项目金额： 25万元

中文摘要： 本项目拟用共价有机骨架（covalent-organic frameworks，COFs）作为催化剂载体，系统研究基于COFs的非均相催化反应。在非均相催化反应的研究中，沸石类催化剂发挥着举足轻重的作用，但是沸石材料大都是微孔结构空腔较小，大大限制它们的广泛应用。近几年发展起来的金属-有机骨架（MOFs）催化剂，具有丰富可调的空腔结构，可以有比较大的底物适用范围，但缺点是稳定性较差且容易解离，较难回收再利用。COFs是一类新型的共价晶态多孔材料，比表面积大、热稳定性高、空腔结构易于调控，因此在非均相催化方面有非常大的潜在应用价值。COFs催化剂开放的催化位点和较大的空腔，有助于提高反应效率拓展底物范围，而且结构稳定，方便回收再利用。申请者计划设计合成一系列具有不同结构特点的COFs催化剂，研究其在非均相催化以及不对称催化方面的应用。这些研究具有重要的理论和应用价值。

中文关键词： 自由基反应；过渡金属催化；C-H活化；绿色有机合成；成环反应

英文摘要： This project focus on the fully analysis on covalent organic frameworks (COFs) based heterogeneous catalysis. Zeolites are very important catalyst supporters in heterogeneous catalytic reactions, while only microporous zeolites were prepared until now. The small pore dimensions drmatically limited their applications in heterogeneous catalysis. Recently, there is a quickly development on the metal-organic frameworks (MOFs) based catalysts with tunable structures and pore sizes. MOFs-type catalysts have wider reagent scopes, while they are not so stable and easy to decompose under certain conditions which make such catalysts poor recyclability. COFs are a new kind of porous crystalline materials that constructed by light elements through covalent bonds. COFs materials have large surface areas, high thermal stability, well-defined cavities and pore sizes, which may have great potential usages in the area of heterogeneous catalysis. The larger channels of COF- catalyst can provide efficient access to the active sites together with fast diffusion for products make such catalyst high reactivity and have broader substrate scope. Due to their robust structure, recycle and reuse become more convenient. With those in mind, the applicant plans to design and synthesis a series of COFs catalysts with different pore sizes and

英文关键词： radical reaction；transition-metal catalysis；C-H activation；green organic synthesis；cyclization