基于属性偏序可视化表示原理的脾虚证方剂配伍规律知识发现方法

项目名称： 基于属性偏序可视化表示原理的脾虚证方剂配伍规律知识发现方法

项目编号： No.61501397

项目类型： 青年科学基金项目

立项/批准年度： 2016

项目学科： 无线电电子学、电信技术

项目作者： 孟辉

作者单位： 燕山大学

项目金额： 19万元

中文摘要： 脾虚证因其多发性一直是医学研究的重要课题。方剂是中医治病的主要形式和手段，是中医辨证论治的具体体现。方剂配伍规律研究是方剂学的核心问题，利用现代科学技术研究脾虚证用药方剂配伍规律及量效关系，提高脾虚证诊治的客观性和准确性，具有非常重要的意义。.本项目以传统中医方剂配伍理论为切入点，提出一种基于属性偏序可视化表示原理的，用于脾虚证方剂配伍规律研究的知识发现新方法。主要学术思想是：以传统中医药理论为依据，以药物数据的规范量化处理为基础，采用分层优化形式背景方法，建立基于属性偏序结构图的方剂配伍知识表示和发现新理论。.本项目将偏序理论与中药方剂配伍规律研究相结合，创新性地将方剂组成信息表现在图形上，并从中发现方剂配伍规律特征，为中医药理论研究提供新的科学手段。预实验表明该方法可从偏序结构图中得到相关方剂的完备知识体系，并发现新的方剂配伍知识。这对于传统中药方剂配伍科学知识发现具有重要意义。

中文关键词： 属性偏序；方剂配伍；可视化；知识发现；脾虚证

英文摘要： Spleen asthenia syndrome is a significant medical study because of its multiple. Prescription is the main approach of treatment in traditional Chinese medicine(TCM), which reflects the theory of syndrome differentiation treatment. The study on the law of prescription compatibility is a research focused on prescription.It is significant to apply the modern science and technology to the research on the law of prescription compatibility and dose-effect relationship of spleen asthenia syndrome in order to enhance the objectivity and accuracy of spleen asthenia syndrome treatment..Based on prescription compatibility theory of TCM, this project puts forward a new theory of attribute partial ordered visualization applied to the compatible prescription of spleen asthenia syndrome. The main academic thought is that: on the basis of the theory of TCM and normalization of drug data processing, the research takes the approach of hierarchical optimization, and theorizes knowledge representation and knowledge discovery method for compatibility of prescription with the application of attribute partial ordered structure diagram..This project combines partial ordered theory with the study on the law of prescription compatibility. With the innovative application of visual diagram to the representation of prescription, the law and feature of prescription compatibility is discovered. It provides the new scientific research method of TCM. Pre-experiment indicates that it can obtain the complete knowledge system of corresponding prescription from partial ordered structure diagram, and discover new law of compatibility knowledge. This research has great significance in scientific knowledge discovery of prescription compatibility of TCM.

英文关键词： attribute partial ordered;prescription compatibility;visualization;knowledge discovery;spleen asthenia syndrome