This paper deals with the GMANOVA model with a matrix of polynomial basis functions as a within-individual design matrix. The model involves two model selection problems: the selection of explanatory variables and the selection of the degrees of the polynomials. The two problems can be uniformly addressed by hierarchically incorporating zeros into the vectors of regression coefficients. Based on this idea, we propose hierarchical overlapping group Lasso (HOGL) to perform the variable and degree selections simultaneously. Importantly, when using a polynomial basis, fitting a highdegree polynomial often causes problems in model selection. In the approach proposed here, these problems are handled by using a matrix of orthonormal basis functions obtained by transforming the matrix of polynomial basis functions. Algorithms are developed with optimality and convergence to optimize the method. The performance of the proposed method is evaluated using numerical simulation.
翻译:本文研究以多项式基函数矩阵作为个体内设计矩阵的GMANOVA模型。该模型涉及两个模型选择问题:解释变量的选择与多项式次数的选择。这两个问题可通过在回归系数向量中分层引入零元素来统一处理。基于这一思路,我们提出分层重叠群组套索(HOGL)方法,以同时实现变量选择与次数选择。需要特别指出的是,当使用多项式基时,拟合高次多项式常会导致模型选择问题。本文提出的方法通过将多项式基函数矩阵转换为正交基函数矩阵来处理这些问题。我们开发了具有最优性与收敛保证的算法来优化该方法,并通过数值模拟评估了所提方法的性能。