Artificial intelligence is undergoing a profound transition from a computational instrument to an autonomous originator of scientific knowledge. This emerging paradigm, the AI scientist, is architected to emulate the complete scientific workflow-from initial hypothesis generation to the final synthesis of publishable findings-thereby promising to fundamentally reshape the pace and scale of discovery. However, the rapid and unstructured proliferation of these systems has created a fragmented research landscape, obscuring overarching methodological principles and developmental trends. This survey provides a systematic and comprehensive synthesis of this domain by introducing a unified, six-stage methodological framework that deconstructs the end-to-end scientific process into: Literature Review, Idea Generation, Experimental Preparation, Experimental Execution, Scientific Writing, and Paper Generation. Through this analytical lens, we chart the field's evolution from early Foundational Modules (2022-2023) to integrated Closed-Loop Systems (2024), and finally to the current frontier of Scalability, Impact, and Human-AI Collaboration (2025-present). By rigorously synthesizing these developments, this survey not only clarifies the current state of autonomous science but also provides a critical roadmap for overcoming remaining challenges in robustness and governance, ultimately guiding the next generation of systems toward becoming trustworthy and indispensable partners in human scientific inquiry.
翻译:人工智能正经历从计算工具向科学知识自主创造者的深刻转变。这一新兴范式——AI科学家——旨在模拟完整的科学工作流程,从初始假设生成到最终可发表成果的综合,从而有望从根本上重塑科学发现的节奏与规模。然而,这些系统的快速且无序的扩散导致了研究领域的碎片化,掩盖了宏观的方法论原则和发展趋势。本综述通过引入一个统一的六阶段方法论框架,对该领域进行了系统而全面的综合梳理,该框架将端到端的科学过程解构为:文献综述、想法生成、实验准备、实验执行、科学写作与论文生成。通过这一分析视角,我们描绘了该领域从早期基础模块(2022-2023年)到集成闭环系统(2024年),再到当前可扩展性、影响力及人机协作前沿(2025年至今)的演进历程。通过严谨综合这些发展,本综述不仅阐明了自主科学的当前状态,还为克服鲁棒性与治理方面的剩余挑战提供了关键路线图,最终引导下一代系统成为人类科学探究中可信赖且不可或缺的合作伙伴。