We introduce AttriGen, a novel framework for automated, fine-grained multi-attribute annotation in computer vision, with a particular focus on cell microscopy where multi-attribute classification remains underrepresented compared to traditional cell type categorization. Using two complementary datasets: the Peripheral Blood Cell (PBC) dataset containing eight distinct cell types and the WBC Attribute Dataset (WBCAtt) that contains their corresponding 11 morphological attributes, we propose a dual-model architecture that combines a CNN for cell type classification, as well as a Vision Transformer (ViT) for multi-attribute classification achieving a new benchmark of 94.62\% accuracy. Our experiments demonstrate that AttriGen significantly enhances model interpretability and offers substantial time and cost efficiency relative to conventional full-scale human annotation. Thus, our framework establishes a new paradigm that can be extended to other computer vision classification tasks by effectively automating the expansion of multi-attribute labels.
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