Guidance methods have demonstrated significant improvements in cross-modal audio generation, including text-to-audio (T2A) and video-to-audio (V2A) generation. The popularly adopted method, classifier-free guidance (CFG), steers generation by emphasizing condition alignment, enhancing fidelity but often at the cost of diversity. Recently, autoguidance (AG) has been explored for audio generation, encouraging the sampling to faithfully reconstruct the target distribution and showing increased diversity. Despite these advances, they usually rely on a single guiding principle, e.g., condition alignment in CFG or score accuracy in AG, leaving the full potential of guidance for audio generation untapped. In this work, we explore enriching the composition of the guidance method and present a mixture-of-guidance framework, AudioMoG. Within the design space, AudioMoG can exploit the complementary advantages of distinctive guiding principles by fulfilling their cumulative benefits. With a reduced form, AudioMoG can consider parallel complements or recover a single guiding principle, without sacrificing generality. We experimentally show that, given the same inference speed, AudioMoG approach consistently outperforms single guidance in T2A generation across sampling steps, concurrently showing advantages in V2A, text-to-music, and image generation. These results highlight a "free lunch" in current cross-modal audio generation systems: higher quality can be achieved through mixed guiding principles at the sampling stage without sacrificing inference efficiency. Demo samples are available at: https://audio-mog.github.io.
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